Double Whammy

Congratulations to Dr Christophe Lalaurie who has had 2 papers published in as many weeks!

Firstly he played a crucial role in this simulation of the globular head of C1q (With Nicole Rodgers first author from her BSc). This paper showed a potential correlation between C1q's ability to bind CRP, and temperature, suggesting a potential energy window for interaction.

https://doi.org/10.1007/s00894-025-06464-y

Before publishing a comprehensive simulation of B2GPI with a lot of help from our friends at the Delcea Lab in Greifswald (https://biochemie.uni-greifswald.de/en/forschung/forschung-in-den-arbeitskreisen/ordner-aks-lehrstuehle/biophysikalische-chemie/prof-dr-mihaela-delcea/) and Prof. Paul Dalby here at UCL (https://profiles.ucl.ac.uk/8354-paul-dalby).

This shows the differences in the unravelling of the circular form of B2GPI between the wild-type and the plasmin clipped version. Its a great paper with some wonderfully developed methods even if we do say so ourselves!

https://doi.org/10.1016/j.yjsbx.2025.100135

Well done Christophe, Nicole, The Delcea Lab, Prof. Dalby and everyone involved!